Welcome to QMS BP a dynamic publication series by the SCTO’s Auditing Platform. Our mission is to foster a culture of continuous improvement and knowledge exchange about quality management systems and relevant best practices (QMS BP) for clinical research infrastructures. Building on our extensive experience within the SCTO’s Auditing Platform with internal audits, quality assessments, and vendor audits, we offer in each issue of QMS BP invaluable insights into common QMS issues we have observed, explain why they require attention, and provide recommendations for actions your organisation can take.